apalutamide will lessen the level or impact of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with prescription drugs which can be CYP3A4 substrates may end up in reduce exposure to these drugs.The regulation of modafinil to be a
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